Tuesday, October 27, 2020

Mitochondrial Eve and the metamorphosis of human being

When I heard about the Corona virus first time few months ago, I tried to understand what is a virus in the first place and how it differs from a bacteria? I soon realized I did not have foundational knowledge needed to understand this in detail, so began my attempt to make up for the knowledge deficit of microbiology. To understand the biochemical reactions and the building elements of a cell, I had to learn chemistry also in detail. I had to log on to Khan Academy for basic courses in Science and order new books to learn the concepts and fundamentals and also bring out the books already available in my book shelf to the reading table. This has kept me busy for the past few months. And I thought of sharing a new thing I learnt about - the concept of "Mitochondrial Eve". You can google the term and get better answers but I still would like to describe in my own terms.

We, human beings inherit the chromosomes from both of our parents, one pair each from father and mother. Though the genetic information comes from both of them, other cellular structural components (like the membrane structures, cytoplasm, mitochondria, lysosome etc.) comes only from mother. What is interesting is, one of the components - mitochondria has its own genetic structure and it only comes from mother. That makes it easier to track maternal ancestry. As you go backwards in the timescale, the number of mothers reduce and around 200,00 years ago, it stops at a single mother - biologists named her Mitochondrial Eve or the mother of humankind. That gives us a reference to study many other things. Like how much of  biological features began transforming us from cave dwellers into present day human beings. Those things let us discuss in the future posts.

Friday, October 23, 2020

Motivational world of Podcasts

Let me tell how all this started. I have been walking as a regular exercise consistently at least for an hour everyday for the past one year. Initially I had fellow walkers walking along with with me. But they had no consistent routine or my time did not match theirs. And then came the rainy season. That did not let me go far away from home and I have to make rounds nearby. And during those walks, I would use my free hands to make phone calls I had to make but they won't last long for an hour and there won't be any need to make calls everyday. 

So I was looking for listening to something as I walked. I was used to watching on youtube - 'Talks at Google', I observed that the same is available as podcast. Similarly 'Farnam Street' blogger has his own podcast. That was nice and interesting. As I started exploring further, I hit the goldmine - Naval. I was so absorbed listening to him and re-listening to him on his podcasts. That accompanied my walks for couple of weeks. In fact, listening to him was so wonderful, my walks became longer. Than I got hooked up to other podcasts - one by Robert Greene, one of my favorite authors, then "Knowledge Project" by Shane Parrish, and now going through "Masters of Scale with Reid Hoffman".  They reduced my reading time but I was able to absorb the information, knowledge, insights offered in these podcasts with almost same intensity of reading. There is one Kannada story channel "ಕೇಳಿರೊಂದು ಕಥೆಯ" too, which I play for my 4 year old son for bedtime stories.

As I share with you always the things that inspire me and keep my mind occupied, I thought I can't keep away from sharing this too.

Here are the links to podcasts:

Naval: https://podcasts.google.com/feed/aHR0cHM6Ly9uYXZhbC5saWJzeW4uY29tL3Jzcw?sa=X&ved=2ahUKEwizzvWKksvsAhXy8zgGHTKJDacQ9sEGegQIARAK
 
Robert Greene Mentoring You: https://podcasts.google.com/feed/aHR0cHM6Ly93d3cuc3ByZWFrZXIuY29tL3Nob3cvNDUyMDEzOS9lcGlzb2Rlcy9mZWVk?sa=X&ved=2ahUKEwizzvWKksvsAhXy8zgGHTKJDacQ9sEGegQIARAI

The Knowledge Project with Shane Parrish: https://podcasts.google.com/feed/aHR0cHM6Ly90aGVrbm93bGVkZ2Vwcm9qZWN0LmxpYnN5bi5jb20vcnNz?sa=X&ved=2ahUKEwizzvWKksvsAhXy8zgGHTKJDacQ9sEGegQIARAJ

Masters of Scale with Reid Hoffman: https://podcasts.google.com/feed/aHR0cHM6Ly9yc3MuYXJ0MTkuY29tL21hc3RlcnMtb2Ytc2NhbGU?sa=X&ved=2ahUKEwizzvWKksvsAhXy8zgGHTKJDacQ9sEGegQIARAC

ಕೇಳಿರೊಂದು ಕಥೆಯ: https://podcasts.google.com/feed/aHR0cDovL2tlbGlyb25kdWthdGhleWEub3JnL3Jzcw?sa=X&ved=2ahUKEwizzvWKksvsAhXy8zgGHTKJDacQ9sEGegQIARAL